STAM2
Sign in to saveAlso known as Hbp, STAM2A, STAM2B, signal transducing adaptor molecule 2
gen de la especie Homo sapiens
Gene data
STAM2- Name
- signal transducing adaptor molecule 2
- Type
- protein-coding
- Position
- 152,116,801–152,175,781 (−)
- Aliases
- Hbp, STAM2A, STAM2B
- Ensembl
- ENSG00000115145
- RefSeq RNA
- NM_005843.6
- RefSeq protein
- NP_005834.4
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
signal transducing adaptor molecule 2
- Symbol
- STAM2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:152,116,801-152,175,781
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein STAM2 PDB 1x2q.png
Show 7 more facts
- HomoloGene ID
- 68490
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10254
- genomic end
- 152175763
- genomic start
- 152973315
- chromosome
- human chromosome 2
- cytogenetic location
- 2q23.3
Sources (4)
via Wikidata · CC0