Also known as HRS, hepatocyte growth factor-regulated tyrosine kinase substrate
protein-coding gene in the species Homo sapiens
Gene data
HGS- Name
- hepatocyte growth factor-regulated tyrosine kinase substrate
- Type
- protein-coding
- Position
- 81,683,326–81,703,138 (+)
- Aliases
- HRS
- Ensembl
- ENSG00000185359
- RefSeq RNA
- NM_004712.5
- RefSeq protein
- NP_004703.1
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
hepatocyte growth factor-regulated tyrosine kinase substrate
- Symbol
- HGS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,683,326-81,703,138
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PDB 2d3g EBI.jpg
Show 7 more facts
- HomoloGene ID
- 37954
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9146
- genomic end
- 79670168
- genomic start
- 79650356
- chromosome
- human chromosome 17
- cytogenetic location
- 17q25.3
Sources (3)
via Wikidata · CC0