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GeneQ18033869· pop 5· linked from 15 articles

Also known as HRS, hepatocyte growth factor-regulated tyrosine kinase substrate

protein-coding gene in the species Homo sapiens

Gene data

HGS
Name
hepatocyte growth factor-regulated tyrosine kinase substrate
Type
protein-coding
Aliases
HRS

The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010].

via MyGene.info

Wikidata facts

Image
PDB 2d3g EBI.jpg
Show 5 more facts
HomoloGene ID
37954
genomic end
79670168
genomic start
79650356
cytogenetic location
17q25.3
Sources (3)

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