STAU2

Also known as 39K2, 39K3, staufen double-stranded RNA binding protein 2

Double-stranded RNA-binding protein Staufen homolog 2 is a protein that in humans is encoded by the STAU2 gene.

Gene data

STAU2

Name: staufen double-stranded RNA binding protein 2
Type: protein-coding
Position: 73,420,369–73,747,708 (−)
Aliases: 39K2, 39K3
Ensembl: ENSG00000040341
RefSeq RNA: NM_001164380.2, NM_001164381.2, NM_001164382.2, NM_001164383.2, NM_001164384.2
RefSeq protein: NP_001157852.1, NP_001157853.1, NP_001157854.1, NP_001157855.1, NP_001157856.1

Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].