SV2B
Sign in to saveAlso known as HsT19680, synaptic vesicle glycoprotein 2B
Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.
Gene data
SV2B- Name
- synaptic vesicle glycoprotein 2B
- Type
- protein-coding
- Position
- 91,099,700–91,302,565 (+)
- Aliases
- HsT19680, SLC22B2
- Ensembl
- ENSG00000185518
- RefSeq RNA
- NM_001167580.3, NM_001323031.2, NM_001323032.3, NM_001323033.3, NM_001323034.3
- RefSeq protein
- NP_001161052.1, NP_001309960.1, NP_001309961.1, NP_001309962.1, NP_001309963.1
This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
synaptic vesicle glycoprotein 2B
- Symbol
- SV2B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:91,099,700-91,302,565
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.
==See also== SV2A
Excerpted from Wikipedia’s “SV2B” article, available under the CC BY-SA 4.0 licence.