File:Treponema_pallidum_Bacteria_(Syphilis)_(cropped).jpg · Wikimedia Commons · See Wikimedia Commons
سیفیلیس
Sign in to saveAlso known as syphilitic chancre, great pox
Syphilis () is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary. The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter), though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. Latent syphilis has no symptom
OverviewAI-generated
Syphilis is a subject with a Commons category of the same name. The disease has a minimal incubation period in humans of 9 and a maximal incubation period of 90. Its disease burden is recorded as 7038641.
In academic literature, PubMed lists a count of 43797 for the query syphilis. Additionally, the subject is referenced by 2,359 other encyclopedia articles.
Synthesized by Vinony from 8 facts across 3 sources: Wikidata, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Medical condition (new).name
- Syphilis
- Medical condition (new).image
- Treponema pallidum Bacteria (Syphilis) (cropped).jpg
- Medical condition (new).caption
- Colorized electron micrograph of Treponema pallidum bacteria, 2022
- Medical condition (new).field
- Infectious disease
- Medical condition (new).symptoms
- Firm, painless, non-itchy skin ulcer
- Medical condition (new).causes
- Treponema pallidum, usually spread by sexual intercourse
- Medical condition (new).diagnosis
- Blood tests, dark field microscopy of infected fluid
- Medical condition (new).differential
- Many other diseases
- Medical condition (new).prevention
- Condoms, Long-term monogamous relationships
- Medical condition (new).treatment
- Antibiotics
- Medical condition (new).frequency
- 45.4 million / 0.6% (2015, global)
- Medical condition (new).deaths
- 107,000 (2015, global)
via Wikipedia infobox
Research
43,797 papers- Syphilis: A Review.ReviewJAMA · 2025Chevalier FJ, Bacon O, Johnson KA et al.DOI: 10.1001/jama.2025.17362
- Syphilis in Pregnancy and Congenital Syphilis.ReviewRhode Island medical journal (2013) · 2024d'Hemecourt K, Santos E, Guerina N et al.
- Syphilis in pregnancy: an ongoing public health threat.ReviewAmerican journal of obstetrics and gynecology · 2022Eppes CS, Stafford I, Rac MDOI: 10.1016/j.ajog.2022.07.041
- Ocular syphilis.Clinical & experimental optometry · 2021Tsan GL, Claiborne RTDOI: 10.1080/08164622.2021.1906848
- Syphilis.ReviewSeminars in perinatology · 1998Hollier LM, Cox SMDOI: 10.1016/s0146-0005(98)80021-9
- [Syphilis].ReviewPresse medicale (Paris, France : 1983) · 2013Dupin N, Farhi DDOI: 10.1016/j.lpm.2012.09.024
- Syphilis in Children.ReviewInfectious disease clinics of North America · 2018Heston S, Arnold SDOI: 10.1016/j.idc.2017.11.007
- The resurgence of syphilis in Australia.ReviewAustralian journal of general practice · 2024Phua G, White CDOI: 10.31128/AJGP-08-23-6943
via PubMed
Wikidata facts
- Instance of
- sexually transmitted infection
- Subclass of
- disease
- Image
- Treponema pallidum.jpg
Show 14 more facts
- topic's main category
- Category:Syphilis
- minimal incubation period in humans
- 9
- maximal incubation period in humans
- 90
- Commons category
- Syphilis
- health specialty
- dermatology
- has cause
- Treponema pallidum
- disease burden
- 7038641
- exact match
- identifiers.org/doid/DOID:4166
- medical examination
- polymerase chain reaction
- different from
- Pau
- drug or therapy used for treatment
- doxycycline
- disease transmission process
- sexually transmitted infection
- P8168
- Kamochi Shrine
- facet of
- women's health
Sources (6)
via Wikidata · CC0
Gallery (48)
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