TCIM

Name

transcriptional and immune response regulator

Type

protein-coding

Position

40,153,482–40,155,310 (+)

Aliases

C8orf4, TC-1, TC1

Ensembl

ENSG00000176907

RefSeq RNA

NM_020130.5

RefSeq protein

NP_064515.2

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011].

via MyGene.info

Gene · Ensembl

transcriptional and immune response regulator

Symbol

TCIM

Biotype

Protein coding

Organism

Homo sapiens

Location

8:40,153,482-40,155,310

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

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