TCIM
Sign in to saveAlso known as TC-1, TC1, C8orf4, chromosome 8 open reading frame 4, transcriptional and immune response regulator
TCIM is a protein that in humans is encoded by the TCIM gene.
Gene data
TCIM- Name
- transcriptional and immune response regulator
- Type
- protein-coding
- Position
- 40,153,482–40,155,310 (+)
- Aliases
- C8orf4, TC-1, TC1
- Ensembl
- ENSG00000176907
- RefSeq RNA
- NM_020130.5
- RefSeq protein
- NP_064515.2
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
transcriptional and immune response regulator
- Symbol
- TCIM
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:40,153,482-40,155,310
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
TCIM is a protein that in humans is encoded by the TCIM gene.
== Function ==
Excerpted from Wikipedia’s “TCIM” article, available under the CC BY-SA 4.0 licence.