Gene data
TECTA- Name
- tectorin alpha
- Type
- protein-coding
- Position
- 121,101,243–121,191,490 (+)
- Aliases
- DFNA12, DFNA8, DFNB21
- Ensembl
- ENSG00000109927
- RefSeq RNA
- NM_005422.4
- RefSeq protein
- NP_005413.2
The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tectorin alpha
- Symbol
- TECTA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:121,101,243-121,191,490
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 3955
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7007
- genomic end
- 121191490
- genomic start
- 121101243
- chromosome
- human chromosome 11
- cytogenetic location
- 11q23.3
- genetic association
- nonsyndromic deafness
Sources (7)
via Wikidata · CC0