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telcagepant

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Also known as MK 0974, MK-0974, MK0974

Telcagepant (INN; development code MK-0974) is a calcitonin gene-related peptide receptor antagonist which was an investigational drug for the acute treatment and prevention of migraine, developed by Merck & Co.

Wikidata facts

Mass
566.206
Show 5 more facts
chemical formula
C₂₆H₂₇F₅N₆O₃
canonical SMILES
C1CC(C(=O)N(CC1C2=C(C(=CC=C2)F)F)CC(F)(F)F)NC(=O)N3CCC(CC3)N4C5=C(NC4=O)N=CC=C5
isomeric SMILES
C1C[C@H](C(=O)N(C[C@@H]1C2=C(C(=CC=C2)F)F)CC(F)(F)F)NC(=O)N3CCC(CC3)N4C5=C(NC4=O)N=CC=C5
Commons category
Telcagepant
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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Telcagepant (INN; development code MK-0974) is a calcitonin gene-related peptide receptor antagonist which was an investigational drug for the acute treatment and prevention of migraine, developed by Merck & Co.

In the acute treatment of migraine, it was found to have equal efficacy to rizatriptan and zolmitriptan.

Excerpted from Wikipedia’s “telcagepant” article, available under the CC BY-SA 4.0 licence.

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