Structure via PubChem · Public domain (PubChem)
tezacitabine
Sign in to saveAlso known as tezacitabine anhydrous
Tezacitabine is a ribonucleotide reductase inhibitor. It is a synthetic purine nucleoside analogue with potential antineoplastic activity. It is used in synthetic DNA.
Chemical data
- Formula
- C10H12FN3O4
- Molecular weight
- 257.22 g/mol
- IUPAC name
- 4-amino-1-[(2R,3E,4S,5R)-3-(fluoromethylidene)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- SMILES
- C1=CN(C(=O)N=C1N)[C@H]2/C(=C/F)/[C@@H]([C@H](O2)CO)O
- InChIKey
- GFFXZLZWLOBBLO-ASKVSEFXSA-N
- XLogP
- -2.3
- Polar surface area
- 108 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 257.081
Show 3 more facts
- chemical formula
- C₁₀H₁₂FN₃O₄
- isomeric SMILES
- C1=CN(C(=O)N=C1N)[C@H]2/C(=C/F)/[C@@H]([C@H](O2)CO)O
- canonical SMILES
- C1=CN(C(=O)N=C1N)C2C(=CF)C(C(O2)CO)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Tezacitabine is a ribonucleotide reductase inhibitor. It is a synthetic purine nucleoside analogue with potential antineoplastic activity. It is used in synthetic DNA.
==References==
Excerpted from Wikipedia’s “tezacitabine” article, available under the CC BY-SA 4.0 licence.