TIMM44
Sign in to saveAlso known as TIM44, translocase of inner mitochondrial membrane 44
Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the TIMM44 gene.
Gene data
TIMM44- Name
- translocase of inner mitochondrial membrane 44
- Type
- protein-coding
- Aliases
- TIM44
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. [provided by RefSeq, Jul 2016].
via MyGene.info
Gene · Ensembl
translocase of inner mitochondrial membrane 44
- Symbol
- TIMM44
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:7,926,715-7,943,773
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TIMM44 PDB 2cw9.png
Show 5 more facts
- HomoloGene ID
- 4631
- exact match
- identifiers.org/ncbigene/10469
- genomic end
- 7943667
- genomic start
- 7991603
- cytogenetic location
- 19p13.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Interactions
- See also
- References
- Further reading
- External links
Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the TIMM44 gene.
==Interactions== TIMM44 has been shown to interact with ARAF.