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EntityQ21098889· pop 5· linked from 3 articles

Also known as MA-1, TAS-1-462

Tipiracil is a drug used in the treatment of cancer. It is approved for use in form of the combination drug trifluridine/tipiracil for the treatment of unresectable advanced or recurrent colorectal cancer.

Wikidata facts

Mass
242.057053
Has use
medication
Show 4 more facts
chemical formula
C₉H₁₁ClN₄O₂
World Health Organisation international non-proprietary name
tipiracil
canonical SMILES
C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl
Commons category
Tipiracil
Sources (3)

via Wikidata · CC0

~3 min read

Encyclopedic overview

8 sections
Contents
  • Adverse effects
  • Interactions
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • Chemistry
  • COVID-19
  • References

Tipiracil is a drug used in the treatment of cancer. It is approved for use in form of the combination drug trifluridine/tipiracil for the treatment of unresectable advanced or recurrent colorectal cancer.

Tipiracil helps maintain the blood concentration of trifluridine by inhibiting the enzyme thymidine phosphorylase which metabolizes trifluridine.

Excerpted from Wikipedia’s “tipiracil” article, available under the CC BY-SA 4.0 licence.

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