TMX4
Sign in to saveAlso known as DJ971N18.2, PDIA14, TXNDC13, thioredoxin related transmembrane protein 4
Thioredoxin-related transmembrane protein 4 also known as thioredoxin domain-containing protein 13 is a protein that in humans is encoded by the TMX4 gene.
Gene data
TMX4- Name
- thioredoxin related transmembrane protein 4
- Type
- protein-coding
- Position
- 7,976,690–8,019,829 (−)
- Aliases
- DJ971N18.2, PDIA14, TXNDC13
- Ensembl
- ENSG00000125827
- RefSeq RNA
- NM_021156.4
- RefSeq protein
- NP_066979.2
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017].
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
thioredoxin related transmembrane protein 4
- Symbol
- TMX4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:7,976,690-8,019,829
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 10901
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/56255
- genomic end
- 8019805
- genomic start
- 7977346
- chromosome
- human chromosome 20
- cytogenetic location
- 20p12.3
- expressed in
- middle temporal gyrus
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Thioredoxin-related transmembrane protein 4 also known as thioredoxin domain-containing protein 13 is a protein that in humans is encoded by the TMX4 gene.
==References==
Excerpted from Wikipedia’s “TMX4” article, available under the CC BY-SA 4.0 licence.