Transferrin receptor 2
Sign in to saveAlso known as transferrin receptor protein 2, TFR2
mammalian protein found in Homo sapiens
Protein · UniProt
Transferrin receptor protein 2
- Gene
- TFR2
- Organism
- Homo sapiens (Human)
- Length
- 801 aa
- Molecular mass
- 88,755 Da
- Evidence
- 1: Evidence at protein level
Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation
Alternative splicingCell membraneCytoplasmDisease variantDisulfide bondGlycoproteinMembraneProteomics identification
View on UniProt →
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
4 registered- PHASE1/PHASE2COMPLETEDPROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCLCytomX Therapeutics · NCT03543813
- NACOMPLETEDIs Iron Deficiency the Cause of Anemia Among Women in Cambodia?University of British Columbia · NCT02481375
- NACOMPLETEDMitochondrial Effects of C18:0 Supplementation in HumansUniversity Hospital Heidelberg · NCT02957838
- PHASE1COMPLETEDMonoclonal Antibody Therapy in Treating Patients With Advanced CancerUniversity of Arizona · NCT00003082
Wikidata facts
- Instance of
- protein
Show 2 more facts
- cell component
- plasma membrane
- found in taxon
- Homo sapiens
Sources (2)
via Wikidata · CC0