Structure via PubChem · Public domain (PubChem)
Tripamide
Sign in to saveAlso known as N-[(1R,2R,6S,7S)-4-azatricyclo[5.2.1.02,6]decan-4-yl]-4-chloro-3-sulfamoylbenzamide
Tripamide (INN) is a diuretic.
Chemical data
- Formula
- C16H20ClN3O3S
- Molecular weight
- 369.9 g/mol
- IUPAC name
- N-[(1S,2S,6R,7R)-4-azatricyclo[5.2.1.02,6]decan-4-yl]-4-chloro-3-sulfamoylbenzamide
- SMILES
- C1C[C@H]2C[C@@H]1[C@@H]3[C@H]2CN(C3)NC(=O)C4=CC(=C(C=C4)Cl)S(=O)(=O)N
- InChIKey
- UHLOVGKIEARANS-NIFPGPBJSA-N
- XLogP
- 2.6
- Polar surface area
- 101 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
19 papers- Sites of action of tripamide.Clinical pharmacology and therapeutics · 1983
- Antihypertensive and biochemical dose-response study of tripamide.Clinical pharmacology and therapeutics · 1986
- Effect of tripamide on glucose tolerance in patients with hypertension.Clinical pharmacology and therapeutics · 1986
- Multicenter private practice comparison of tripamide and hydrochlorothiazide in the treatment of hypertension.Family practice research journal · 1988
- The influence of hydrochlorothiazide and tripamide on serum and urinary amylase.Journal of clinical pharmacology · 1988
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 369.09139
Show 3 more facts
- chemical formula
- C₁₆H₂₀ClN₃O₃S
- isomeric SMILES
- C1C[C@H]2C[C@@H]1[C@@H]3[C@H]2CN(C3)NC(=O)C4=CC(=C(C=C4)Cl)S(=O)(=O)N
- canonical SMILES
- C1CC2CC1C3C2CN(C3)NC(=O)C4=CC(=C(C=C4)Cl)S(=O)(=O)N
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Tripamide (INN) is a diuretic.
==References==
Excerpted from Wikipedia’s “Tripamide” article, available under the CC BY-SA 4.0 licence.