TRMT12
Sign in to saveAlso known as TRM12, TYW2, tRNA methyltransferase 12 homolog
tRNA wybutosine-synthesizing protein 2 homolog is a protein that in humans is encoded by the TRMT12 gene.
Gene data
TYW2- Name
- tRNA wybutosine-synthesizing protein 2
- Type
- protein-coding
- Position
- 124,450,820–124,462,150 (+)
- Aliases
- TRM12, TRMT12
- Ensembl
- ENSG00000183665
- RefSeq RNA
- NM_017956.4
- RefSeq protein
- NP_060426.2
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
tRNA wybutosine-synthesizing protein 2
- Symbol
- TYW2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:124,450,820-124,462,150
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 32379
- genomic end
- 124462150
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55039
- genomic start
- 125463048
- chromosome
- human chromosome 8
- cytogenetic location
- 8q24.13
- expressed in
- amniotic fluid
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
tRNA wybutosine-synthesizing protein 2 homolog is a protein that in humans is encoded by the TRMT12 gene.
==References==
Excerpted from Wikipedia’s “TRMT12” article, available under the CC BY-SA 4.0 licence.