trophoblast cell
Sign in to saveAlso known as trophoblast, trophoblasts
The trophoblast (from Greek : to feed; and : germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg to become extraembryonic structures that do not directly contribute to the embryo. After blastulation, the trophoblast is contiguous with the ectoderm of the embryo and is referred to as the trophectoderm. After the first differentiati
Key facts
- Embryology.Name
- Trophoblast
- Embryology.Latin
- trophoblastus; massa cellularis externa
- Embryology.Image
- Diagram of Blastocyst stage.png
- Embryology.Caption
- Blastocyst with an inner cell mass and trophoblast.
- Embryology.Days
- 6
- Embryology.GivesRiseTo
- Caul
via Wikipedia infobox
Research
26,042 papers- Molecular characteristics of established trophoblast-derived cell lines.Placenta · 2021
- KLF4 regulates trophoblast function and associates with unexplained recurrent spontaneous abortion.Journal of translational medicine · 2024
- Trophoblast stem cells.Methods in enzymology · 2006
- Human trophoblast in trisomy 21: a model for cell-cell fusion dynamic investigation.Advances in experimental medicine and biology · 2011
- Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts.Scientific reports · 2020
via PubMed
Wikidata facts
Show 1 more fact
- Commons category
- Chorionic villi
Sources (6)
via Wikidata · CC0
~5 min read
Encyclopedic overview
7 sectionsContents
- Structure
- Function
- Clinical significance
- Additional images
- See also
- References
- External links
The trophoblast (from Greek : to feed; and : germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg to become extraembryonic structures that do not directly contribute to the embryo. After blastulation, the trophoblast is contiguous with the ectoderm of the embryo and is referred to as the trophectoderm. After the first differentiation, the cells in the human embryo lose their totipotency because they can no longer form a trophoblast. They become pluripotent stem cells.
== Structure == thumb|left|Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation The trophoblast proliferates and differentiates into two cell layers at approximately six days after fertilization for humans.
Excerpted from Wikipedia’s “trophoblast cell” article, available under the CC BY-SA 4.0 licence.