TTI2

Name

TELO2 interacting protein 2

Type

protein-coding

Position

33,473,386–33,513,185 (−)

Aliases

C8orf41, MRT39

Ensembl

ENSG00000129696

RefSeq RNA

NM_001102401.4, NM_001265581.2, NM_001330505.3, NM_001440381.1, NM_025115.5

RefSeq protein

NP_001095871.1, NP_001252510.1, NP_001317434.1, NP_001427310.1, NP_079391.2

This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance. [provided by RefSeq, May 2013].