Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C21H40N8O6
- Molecular weight
- 500.6 g/mol
- IUPAC name
- (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
- SMILES
- C[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N)O
- InChIKey
- IESDGNYHXIOKRW-YXMSTPNBSA-N
- XLogP
- -7
- Polar surface area
- 252 Ų
- H-bond donors
- 8
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
Research
689 papers- Helminth derivative tuftsin-phopshorylcholine to treat autoimmunity.Autoimmunity reviews · 2024
- Tuftsin - Properties and Analogs.Current medicinal chemistry · 2017
- FcγR-targeted tuftsin clusters rejuvenate macrophages in preclinical sepsis-associated secondary infection.Science translational medicine · 2025
- [Tuftsin].Allergie und Immunologie · 1984
- Tuftsin phosphorylcholine-a novel compound harnessing helminths to fight autoimmunity.Immunologic research · 2018
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 500.307
Show 3 more facts
- chemical formula
- C₂₁H₄₀N₈O₆
- isomeric SMILES
- C[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N)O
- canonical SMILES
- CC(C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)O)N)O
Sources (2)
via Wikidata · CC0
Article · Italiano
La tuftsina è un tetrapeptide (Thr-Lys-Pro-Arg) prodotto principalmente nella milza e sulla superficie delle cellule fagocitarie mediante scissione del dominio Fc dell'immunoglobulina G (IgG).Il suo nome deriva da Tufts University (nei pressi della città di Boston), dove fu isolata nel 1970 dagli scienziati Najjar e Nishioka.
Abstract from DBpedia / Wikipedia · CC BY-SA