UBQLN2

Name

ubiquilin 2

Type

protein-coding

Chromosome

X

Aliases

ALS15, CHAP1, DSK2, HRIHFB2157, N4BP4, PLIC2

This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009].

via MyGene.info

Wikidata facts

Image

Protein UBQLN2 PDB 1j8c.png

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