WD repeat-containing protein 62 is a protein that in humans is encoded by the WDR62 gene.
WD repeat-containing protein 62 is a protein that in humans is encoded by the WDR62 gene.
== Function == WDR62 is a scaffold protein and interacts with different kinases. WDR62 plays a role in mediating activation of the JNK pathway in response to TNFα. This finding might have implications in the research of TNFα related diseases such as autoimmune diseases and cancer. It has been also shown that WDR62 upregulation can lead to overproliferation of glia cells and potentially glioma and this is coupled with an upregulation in AURKA, AKT, MYC and PI3K signalling.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).