WFIKKN1
Sign in to saveAlso known as C16orf12, RJD2, WFDC20A, WFIKKN, WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 is a protein that is encoded by the WFIKKN1 gene. when found in humans.
In the Vinony graph
Within Vinony's link graph, WFIKKN1 is referenced by 5 other articles, and connects out to Q180686, human chromosome 16 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 16.
Its subject is documented across 6 Wikipedia language editions.
Gene data
WFIKKN1- Name
- WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
- Type
- protein-coding
- Position
- 629,239–634,117 (+)
- Aliases
- C16orf12, RJD2, WFDC20A, WFIKKN
- Ensembl
- ENSG00000127578
- RefSeq RNA
- NM_053284.3
- RefSeq protein
- NP_444514.1
This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
- Symbol
- WFIKKN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:629,239-634,117
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein WFIKKN1 PDB 2ddi.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/117166
- HomoloGene ID
- 14244
- genomic end
- 634117
- genomic start
- 679239
- cytogenetic location
- 16p13.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 is a protein that is encoded by the WFIKKN1 gene. when found in humans.
This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.
Excerpted from Wikipedia’s “WFIKKN1” article, available under the CC BY-SA 4.0 licence.