Withanolides
Sign in to saveAlso known as withanolide, Withanolide
thumb|Withaferin A thumb|Salpichrolid A thumb|Nicandrenon-1 thumb|Ixocarpalacton A Withanolides are a group of at least 300 naturally occurring steroids built on an ergostane skeleton. They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo.
Research
1,498 papers- Withanolides: Promising candidates for cancer therapy.Phytotherapy research : PTR · 2024
- Quantifying Withanolides in Plasma: Pharmacokinetic Studies and Analytical Methods.Nutrients · 2024
- Biosynthesis of the triterpenoid withanolides in Withaniasomnifera.Current opinion in plant biology · 2024
- Withanolides from the genus Physalis: a review on their phytochemical and pharmacological aspects.The Journal of pharmacy and pharmacology · 2020
- Withanolides as Prospective Drug Candidates: Production and Therapeutic Applications-A Review.Planta medica · 2025
via PubMed
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- Withanolides
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thumb|Withaferin A thumb|Salpichrolid A thumb|Nicandrenon-1 thumb|Ixocarpalacton A Withanolides are a group of at least 300 naturally occurring steroids built on an ergostane skeleton. They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo.
Structurally, withanolides consist of a steroid backbone bound to a lactone or one of its derivatives; they are produced via oxidation of steroids. It remains unknown to what end withanolides are produced; they may act as a deterrent for feeding insect larvae and other herbivores.