(Z)-Toremifene
Sign in to saveAlso known as Farestone®, FC-1157a, Toremifenum, Toremifeno, Toremifene, 2-{4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy}-N,N-dimethylethanamine, toremifene
Toremifene, sold under the brand name Fareston among others, is a medication which is used in the treatment of advanced breast cancer in postmenopausal women. It is taken by mouth.
Research
14 papers- (131)I-Labeled [Z]-2-[4-(1,2-diphenyl-1-di-butenyl)-phenoxy]-N,N-dimethylethanamine.2004
- Mass spectrometric characterization of toremifene metabolites in human urine by liquid chromatography-tandem mass spectrometry with different scan modes.The Analyst · 2011
- Toremifene interacts with and destabilizes the Ebola virus glycoprotein.Nature · 2016
- Mass spectrometric characterization of urinary toremifene metabolites for doping control analyses.Journal of chromatography. A · 2011
- Toremifene metabolism in rat, mouse and human liver microsomes: identification of alpha-hydroxytoremifene by LC-MS.Biomedical chromatography : BMC · 2002
via PubMed
~11 min read
Encyclopedic overview
22 sectionsContents
- Medical uses
- Available forms
- Side effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Availability
- Research
- Phase III Trial Results
- References
- Further reading
- External links
Toremifene, sold under the brand name Fareston among others, is a medication which is used in the treatment of advanced breast cancer in postmenopausal women. It is taken by mouth.
Side effects of toremifene include hot flashes, sweating, nausea, vomiting, dizziness, vaginal discharge, and vaginal bleeding. It can also cause blood clots, irregular heartbeat, cataracts, visual disturbances, elevated liver enzymes, endometrial hyperplasia, and endometrial cancer. High blood calcium levels can occur in women with bone metastases.
Excerpted from Wikipedia’s “(Z)-Toremifene” article, available under the CC BY-SA 4.0 licence.
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