Neurotrophic factors

protein-coding gene in the species Homo sapiens

mammalian protein found in Homo sapiens

signal protein produced by cells that stimulates vasculogenesis and angiogenesis

mammalian protein found in Homo sapiens

mammalian protein found in Homo sapiens

Neurotrophins are a family of proteins that induce the survival, development, and function of neurons.

Cenegermin, sold under the brand name Oxervate, also known as recombinant human nerve growth factor, is a recombinant form of human nerve growth factor. Cenegermin is a peripherally selective agonist of the tropomyosin receptor kinase A (TrkA) and low-affinity nerve growth factor receptor (p75NTR).

Neuregulins are a family of four structurally related proteins that are part of the EGF family of proteins. These proteins have been shown to have diverse functions in the development of the nervous system and play multiple essential roles in vertebrate embryogenesis including: cardiac development, Schwann cell and oligodendrocyte differentiation, some aspects of neuronal development, as well as the formation of neuromuscular synapses.

Ephrins (also known as ephrin ligands or Eph family receptor interacting proteins) are a family of proteins that serve as the ligands of the Eph receptor. Eph receptors in turn compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs).

Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene.

protein-coding gene in the species Homo sapiens

Amdiglurax (), also known by its former developmental code names ALTO-100 and NSI-189 (short for "NeuralStem Inc. 189"), is a drug described as a hippocampal neurogenesis stimulant and indirect brain-derived neurotrophic factor (BDNF) modulator which is under development for the treatment of major depressive disorder (MDD), bipolar depression, and post-traumatic stress disorder (PTSD). There has also been interest in amdiglurax for possible treatment of cognitive impairment and neurodegeneration. It is taken by mouth.

family of biomolecules that support the growth, survival, and differentiation of both developing and mature neurons

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene.