NRG1

Name

neuregulin 1

Type

protein-coding

Position

31,639,222–32,855,666 (+)

Aliases

ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF

Ensembl

ENSG00000157168

RefSeq RNA

NM_001159995.3, NM_001159996.3, NM_001159999.3, NM_001160001.3, NM_001160002.2

RefSeq protein

NP_001153467.1, NP_001153468.1, NP_001153471.1, NP_001153473.1, NP_001153474.1

The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016].

via MyGene.info

Gene · Ensembl

neuregulin 1

Symbol

NRG1

Biotype

Protein coding

Organism

Homo sapiens

Location

8:31,639,222-32,855,666

Strand

Forward (+)

Assembly

GRCh38