Obesity

Obesity is a medical condition, considered by multiple organizations to be a disease, in which excess body fat has accumulated to such an extent that it can have negative effects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apne

loose connective tissue composed mostly of adipocytes

thumb|Der Völler by Georg Emanuel Opiz|Georg Emmanuel Opiz thumb|A woodcut representing gluttony Gluttony (, derived from the Latin gluttire meaning 'to gulp down or swallow') means over-indulgence and over-consumption of anything to the point of waste.

Leptin (from Greek λεπτός leptos, "thin" or "light" or "small"), also known as obese protein, is a protein hormone predominantly made by adipocytes (cells of adipose tissue). Its primary role is likely to regulate long-term energy balance.

reduction of the total body mass

Ghrelin (; or lenomorelin, INN) is a hormone primarily produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach, and is also dubbed the "hunger hormone" because it increases the drive to eat. Blood levels of ghrelin are highest before meals when hungry, returning to lower levels after mealtimes. Ghrelin may help prepare for food intake by increasing gastric motility and stimulating the secretion of gastric acid.

inactive lifestyle with health risks

Adiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels and fatty acid breakdown. In humans, it is encoded by the ADIPOQ gene and is produced primarily in adipose tissue, but also in muscle and even in the brain.

third-heaviest person in history

Bariatrics is a discipline that deals with the causes, prevention, and treatment of obesity, encompassing both obesity medicine and bariatric surgery.

repeated cycles of weight loss followed by weight gain

Resistin, also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1), is a cysteine-rich peptide hormone that is derived from adipose tissue and, in humans, is encoded by the RETN gene.

mammalian protein found in Homo sapiens

behavioral addiction that is characterized by the compulsive consumption of palatable foods despite adverse consequences.

Saudi Arabian man who was the heaviest living person in 2013

type of paraphilia

social movement seeking to change anti-fat bias in social attitudes

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increase in a person's total body mass

considered to be the heaviest living woman in the world and the second heaviest woman in history (after Carol Yager)

Obestatin is a hormone that is produced in specialized epithelial cells of the stomach and small intestine of several animals including humans. Obestatin was originally identified as an anorectic peptide, but its effect on food intake remains controversial.

protein-coding gene in the species Homo sapiens

veterinary disease

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diet with very or extremely low daily food energy consumption

overhanging fat that spills over the waistline of pants or skirts

Fatty acid-binding protein 2 (FABP2), also known as Intestinal-type fatty acid-binding protein (I-FABP), is a protein that in humans is encoded by the FABP2 gene.

mammalian protein found in Homo sapiens

health awareness day

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thumb|upright=1.3|Coronal Image of a TOFI and a Normal Control TOFI (thin-outside-fat-inside) is used to describe lean individuals with a disproportionate amount of fat (adipose tissue) stored in their abdomen. The figure to illustrate this shows two men, both 35 years old, with a BMI of 25 kg/m2. Despite their similar size, the TOFI had 5.86 litres of internal fat, whilst the healthy control had only 1.65 litres.

class of enzymes

ambulance vehicle modified to carry the severely obese.