NAMPT
Sign in to saveAlso known as 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN, nicotinamide phosphoribosyltransferase
protein-coding gene in the species Homo sapiens
Gene data
NAMPT- Name
- nicotinamide phosphoribosyltransferase
- Type
- protein-coding
- Position
- 106,248,298–106,291,225 (−)
- Aliases
- 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN
- Ensembl
- ENSG00000105835
- RefSeq RNA
- NM_005746.3, NM_182790.1, XM_047419699.1, XM_047419700.1, XM_054356984.1
- RefSeq protein
- NP_005737.1, XP_047275655.1, XP_047275656.1, XP_054212959.1, XP_054212960.1
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
nicotinamide phosphoribosyltransferase
- Symbol
- NAMPT
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:106,248,298-106,291,225
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PBEF1 PDB 2g95.png
Show 5 more facts
- HomoloGene ID
- 4201
- exact match
- identifiers.org/ncbigene/10135
- genomic end
- 106285966
- genomic start
- 106248298
- cytogenetic location
- 7q22.3
via Wikidata · CC0