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Category

Sulfones

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sulfone
thumb|150px|right|The structure of a sulfone thumb|Methylsulfonylmethane|Dimethyl sulfone, an example of a sulfone
dimethyl sulfone
Dimethyl sulfone (DMSO2) is an organosulfur compound with the formula . It is also known by several other names including methyl sulfone and (especially in alternative medicine) methylsulfonylmethane (MSM). This colorless solid features the sulfonyl functional group and is the simplest of the sulfones. It is relatively inert chemically and is able to resist decomposition at elevated temperatures. It occurs naturally in some primitive plants, is present in small amounts in many foods and beverages, and is marketed (under the MSM name) as a dietary supplement. It is sometimes used as a cutting a
tinidazole
Tinidazole, sold under the brand name Tindamax among others, is a medication used against infections caused by certain anaerobic bacteria and protozoa. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class.
sulfolane
Sulfolane (also tetramethylene sulfone, systematic name: 1-thiolane-1,1-dione) is an organosulfur compound, formally a cyclic sulfone, with the formula . It is a colorless liquid commonly used in the chemical industry as a solvent for extractive distillation and chemical reactions. Sulfolane was originally developed by the Shell Oil Company in the 1960s as a solvent to purify butadiene. Sulfolane is a polar aprotic solvent, and it is miscible with water.
sulbactam
Sulbactam is a β-lactamase inhibitor. This drug is given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys the antibiotics.
nifurtimox
Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. In Chagas disease it is a second-line option to benznidazole. It is given by mouth.
brinzolamide
Brinzolamide (trade name Azopt) is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
tazobactam
Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt, tazobactam sodium.
dorzolamide
Dorzolamide, sold under the brand name Trusopt among others, is a medication used to treat high pressure inside the eye, including in cases of glaucoma. It is used as an eye drop. Effects begin within three hours and last for at least eight hours. It is also available as the combination dorzolamide/timolol.
lapatinib
Lapatinib (INN), used in the form of lapatinib ditosylate (USAN) (trade names Tykerb and Tyverb marketed by Novartis) is an orally active drug for breast cancer and other solid tumours. It is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathways. It is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 (ErbB2).
3-sulfolene
Sulfolene, or butadiene sulfone is a cyclic organic chemical with a sulfone functional group. It is a white, odorless, crystalline, indefinitely storable solid, which dissolves in water and many organic solvents. The compound is used as a source of butadiene.
polysulfone
thumb|class=skin-invert-image|Polysulfone (PSU) repeating unit. thumb|class=skin-invert-image|Polyethersulfone (PES) repeating unit.
chlormezanone
Chlormezanone (marketed under the brandname Trancopal or Fenaprim) is a drug used as an anxiolytic and a muscle relaxant.
sulfonethylmethane
Trional (Methylsulfonal) is a sedative-hypnotic and anesthetic drug with GABAergic actions. It has similar effects to sulfonal, except it is faster acting.
sulfonmethane
Sulfonmethane (sulfonomethane, sulfonal, acetone diethyl sulfone) is a chemical compound first synthesized by Eugen Baumann in 1888 and introduced as a hypnotic drug by Alfred Kast later on, but now superseded by newer and safer sedatives. Its appearance is either in colorless crystalline or powdered form. In United States, it is scheduled as a Schedule III drug in the Controlled Substances Act.
flubendiamide
Flubendiamide is the first insecticide of the diamide class. It acts on the ryanodine receptor.
amenamevir
Amenamevir (trade name Amenalief) is an antiviral drug used for the treatment of shingles (herpes zoster).
tetronal
Tetronal is a sedative-hypnotic and anesthetic drug with GABAergic actions. It is not as effective as trional.