Structure via PubChem · Public domain (PubChem)
amenamevir
Sign in to saveAlso known as ASP-2151, ASP2151, Amenalief
Amenamevir (trade name Amenalief) is an antiviral drug used for the treatment of shingles (herpes zoster).
Chemical data
- Formula
- C24H26N4O5S
- Molecular weight
- 482.6 g/mol
- IUPAC name
- N-(2,6-dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide
- SMILES
- CC1=C(C(=CC=C1)C)N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CCS(=O)(=O)CC4
- InChIKey
- MNHNIVNAFBSLLX-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 131 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 482.162
Show 2 more facts
- canonical SMILES
- CC1=C(C(=CC=C1)C)N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CCS(=O)(=O)CC4
- chemical formula
- C₂₄H₂₆N₄O₅S
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Amenamevir (trade name Amenalief) is an antiviral drug used for the treatment of shingles (herpes zoster).
It acts as an inhibitor of the zoster virus's helicase–primase complex. Amenamevir was approved in Japan for the treatment of shingles in 2017.
Excerpted from Wikipedia’s “amenamevir” article, available under the CC BY-SA 4.0 licence.