ABTS

Also known as A2BTS, C18H18N4O6S4

In biochemistry, ABTS ('''2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)''') is a chemical compound used to observe the reaction kinetics of specific enzymes. A common use for it is in the enzyme-linked immunosorbent assay (ELISA) to detect the binding of molecules to each other.

Chemical data

Formula: C18H18N4O6S4
Molecular weight: 514.6 g/mol
IUPAC name: (2E)-3-ethyl-2-[(Z)-(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid
SMILES: CCN\1C2=C(C=C(C=C2)S(=O)(=O)O)S/C1=N/N=C\3/N(C4=C(S3)C=C(C=C4)S(=O)(=O)O)CC
InChIKey: ZTOJFFHGPLIVKC-YAFCTCPESA-N
XLogP: 2.5
Polar surface area: 207 Å²
H-bond donors: 2
H-bond acceptors: 10
Formal charge: 0

via PubChem

Research

16,393 papers

Antioxidant activity applying an improved ABTS radical cation decolorization assay.Free radical biology & medicine · 1999
Statistical evaluation of DPPH, ABTS, FRAP, and Folin-Ciocalteu assays to assess the antioxidant capacity of lignins.International journal of biological macromolecules · 2023
ABTS/PP Decolorization Assay of Antioxidant Capacity Reaction Pathways.International journal of molecular sciences · 2020
Enhanced chlorination of diclofenac using ABTS as electron shuttle: Performance, mechanism and applicability.The Science of the total environment · 2024
Electrochemically-functionalized CNT/ABTS nanozyme enabling sensitive and selective voltammetric detection of microalbuminuria.Analytica chimica acta · 2022

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 548.064016488

Show 5 more facts

chemical formula: C₁₈H₁₈N₄O₆S₄
canonical SMILES: CCN1/C(Sc2cc(ccc12)S(O)(=O)=O)=N/N=C/3Sc4cc(ccc4N3CC)S(O)(=O)=O
different from: heavy rescue vehicle
Commons category: ABTS
isomeric SMILES: CCn1/c(=N/N=c2\sc3cc(S(=O)(=O)O)ccc3n2CC)sc2cc(S(=O)(=O)O)ccc21.N.N

Sources (3)

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