cytochrome c, somatic

Protein · UniProt

Cytochrome c

Gene

CYCS

Organism

Homo sapiens (Human)

Length

105 aa

Molecular mass

11,749 Da

Evidence

1: Evidence at protein level

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain

• Cytosolic cytochrome c represses ferroptosis.Cell metabolism · 2025
• Copper metabolism in cell death and autophagy.Autophagy · 2023
• The role of STAT3 in autophagy.Autophagy · 2015
• The multifaceted regulation of mitophagy by endogenous metabolites.Autophagy · 2022
• COX15 deficiency causes oocyte ferroptosis.Proceedings of the National Academy of Sciences of the United States of America · 2024

via PubMed

• COMPLETED
  Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)University of Iowa · NCT02997423
• RECRUITING
  North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)Columbia University · NCT01694940
• COMPLETED
  Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of OutcomeWake Forest University Health Sciences · NCT02440373
• UNKNOWN
  Prognostic Value of Plasma Mitochondrial DNA and Cytochrome C After Cardiac ArrestUniversity Medical Centre Ljubljana · NCT03539497
• RECRUITING
  Ultrastructural Characteristics of Mitochondria in Cardiomyocytes in Heart FailureTomsk National Research Medical Center of the Russian Academy of Sciences · NCT05770349

via ClinicalTrials.gov