ADH6
Sign in to saveAlso known as ADH-5, alcohol dehydrogenase 6 (class V)
Alcohol dehydrogenase 6 is an enzyme that in humans is encoded by the ADH6 gene.
In the Vinony graph
Within Vinony's link graph, ADH6 is referenced by 3 other articles, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Its subject is documented across 4 Wikipedia language editions.
Gene data
ADH6- Name
- alcohol dehydrogenase 6 (class V)
- Type
- protein-coding
- Position
- 99,202,424–99,219,537 (−)
- Aliases
- ADH-5
- Ensembl
- ENSG00000172955
- RefSeq RNA
- NM_000672.4, NM_001102470.2, NR_132990.2
- RefSeq protein
- NP_000663.1, NP_001095940.1
This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
alcohol dehydrogenase 6 (class V)
- Symbol
- ADH6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:99,202,424-99,219,537
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 68077
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/130
- cytogenetic location
- 4q23
- genomic end
- 100140694
- genomic start
- 100123795
- chromosome
- human chromosome 4
- Commons category
- Cinnamyl alcohol dehydrogenase, ADH6
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Alcohol dehydrogenase 6 is an enzyme that in humans is encoded by the ADH6 gene.
This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. The deduced amino acid sequence of the open reading frame of this gene shows about 60% positional identity with other known alcohol dehydrogenases. This gene may have a distinct physiologic function.
Excerpted from Wikipedia’s “ADH6” article, available under the CC BY-SA 4.0 licence.