Structure via PubChem · Public domain (PubChem)
altrenogest
Sign in to saveAltrenogest, sold under the brand names Swinemate and Altren manufactured by Aurora Pharmaceutical and Regumate manufactured by Merck, is a progestin of the 19-nortestosterone group which is widely used in veterinary medicine to suppress or synchronize estrus in horses and pigs. It is available for veterinary use in both Europe (as Regumate) and the United States (as Matrix).
Chemical data
- Formula
- C21H26O2
- Molecular weight
- 310.4 g/mol
- IUPAC name
- (8S,13S,14S,17R)-17-hydroxy-13-methyl-17-prop-2-enyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(CC=C)O
- InChIKey
- VWAUPFMBXBWEQY-ANULTFPQSA-N
- XLogP
- 2.8
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
285 papers- Effects of altrenogest on reproductive performance of gilts and sows: A meta-analysis.Animal reproduction science · 2018
- Pharmacokinetics of altrenogest in gilts.Journal of veterinary pharmacology and therapeutics · 2019
- Altrenogest Supplementation during Early Pregnancy Improves Reproductive Outcome in Pigs.Animals : an open access journal from MDPI · 2022
- Altrenogest affects the development and endocrine milieu of ovarian follicles in prepubertal and mature gilts†.Biology of reproduction · 2020
- Altrenogest treatment reduces the stress response of three-year-old warmblood mares during their initial equestrian training.Domestic animal endocrinology · 2022
via PubMed
Wikidata facts
- Mass
- 310.193
Show 4 more facts
- chemical formula
- C₂₁H₂₆O₂
- canonical SMILES
- CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(CC=C)O
- isomeric SMILES
- C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(CC=C)O
- Commons category
- Altrenogest
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
11 sectionsContents
- Uses
- Veterinary
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- History
- Society and culture
- Generic names
- Brand names
- References
Altrenogest, sold under the brand names Swinemate and Altren manufactured by Aurora Pharmaceutical and Regumate manufactured by Merck, is a progestin of the 19-nortestosterone group which is widely used in veterinary medicine to suppress or synchronize estrus in horses and pigs. It is available for veterinary use in both Europe (as Regumate) and the United States (as Matrix).
==Uses==
Excerpted from Wikipedia’s “altrenogest” article, available under the CC BY-SA 4.0 licence.