Structure via PubChem · Public domain (PubChem)
triamcinolone acetonide
Sign in to saveAlso known as 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17-isopropylidenedioxy-1,4-pregnadiene,3,20-dione, (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide, 9alpha-fluoro-16alpha-17alpha-isopropylidenedioxy-Delta-1-hydrocortisone, 9alpha-fluoro-16alpha-17alpha-isopropyledenedioxyprednisolone, 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione, 9alpha-fluoro-16alpha-hydroxyprednisolone 16alpha,17alpha-acetonide, Triamcinolone 16,17-acetonide
chemical compound
Chemical data
- Formula
- C24H31FO6
- Molecular weight
- 434.5 g/mol
- IUPAC name
- (1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
- SMILES
- C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)CCC5=CC(=O)C=C[C@@]53C)F)O
- InChIKey
- YNDXUCZADRHECN-JNQJZLCISA-N
- XLogP
- 2.5
- Polar surface area
- 93.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1960
- Admin. routes
- parenteral, topical
- Indications
- diabetic retinopathy, osteoarthritis, knee, seasonal allergic rhinitis, pain
via ChEMBL · EBI
Research
8,724 papers- Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema.Drugs · 2022
- Enigma of Intramuscular Triamcinolone Acetonide (Kenalog(®)) Efficacy.Clinical pharmacokinetics · 2023
- Analytical Methods for Triamcinolone Acetonide: An Exploratory Literature Review.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2023
- Triamcinolone acetonide in ocular therapeutics.Survey of ophthalmology · 2007
- Triamcinolone acetonide. A review of its pharmacological properties and therapeutic efficacy in the management of allergic rhinitis.Drugs · 1997
via PubMed
Wikidata facts
- Mass
- 434.21
Show 6 more facts
- chemical formula
- C₂₄H₃₁FO₆
- canonical SMILES
- CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)C
- isomeric SMILES
- C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)CCC5=CC(=O)C=C[C@@]53C)F)O
- subject has role
- immunosuppressive drug
- Commons category
- Triamcinolone acetonide
- legal status (medicine)
- boxed warning
via Wikidata · CC0
Available in 12 languages
via Wikidata sitelinks · CC0