آمدوکسوویر

Also known as Amdoxovir, DAPD

Amdoxovir is a pharmaceutical drug that has undergone research for the treatment of HIV/AIDS. It acts as a nucleoside reverse transcriptase inhibitor (NRTI). The drug was discovered by Raymond F. Schinazi (Emory University) and C.K. Chu (University of Georgia) and developed by RFS Pharma.

Chemical data

Formula: C9H12N6O3
Molecular weight: 252.23 g/mol
IUPAC name: [(2R,4R)-4-(2,6-diaminopurin-9-yl)-1,3-dioxolan-2-yl]methanol
SMILES: C1[C@@H](O[C@@H](O1)CO)N2C=NC3=C(N=C(N=C32)N)N
InChIKey: RLAHNGKRJJEIJL-RFZPGFLSSA-N
XLogP: -1.2
Polar surface area: 134 Å²
H-bond donors: 3
H-bond acceptors: 8
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: HIV infection

via ChEMBL · EBI

Wikidata facts

Mass: 252.097

Show 4 more facts

chemical formula: C₉H₁₂N₆O₃
isomeric SMILES: C1[C@@H](O[C@@H](O1)CO)N2C=NC3=C2N=C(N=C3N)N
canonical SMILES: C1C(OC(O1)CO)N2C=NC3=C2N=C(N=C3N)N
Commons category: Amdoxovir

Sources (2)

via Wikidata · CC0

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via Wikidata sitelinks · CC0