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EntityQ3617574· pop 10· linked from 9 articles

anisindione

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Also known as 2-(P-Methoxyphenyl)-1,3-indandione, 2-para-anisyl-1,3-indandione, 2-p-anisyl-1,3-indandione, 2-(p-methoxyphenyl)indane-1,3-dione, 2-(p-methoxyphenyl)-1,3-indandione, 2-(4-methoxyphenyl)indan-1,3-dione, 2-(4-methoxyphenyl)-1H-indene-1,3(2H)-dione, anisin indandione

Anisindione (brand name Miradon) is a synthetic anticoagulant and an 1,3-indandione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.

Wikidata facts

Mass
252.078644
Has use
medication
Show 6 more facts
chemical formula
C₁₆H₁₂O₃
medical condition treated
pulmonary embolism
canonical SMILES
COC1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O
World Health Organisation international non-proprietary name
anisindione
physically interacts with
Gamma-glutamyl carboxylase
Commons category
Anisindione
Sources (3)

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Encyclopedic overview

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Anisindione (brand name Miradon) is a synthetic anticoagulant and an 1,3-indandione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.

== References ==

Excerpted from Wikipedia’s “anisindione” article, available under the CC BY-SA 4.0 licence.

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