antidiuretic
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An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, opposing diuresis. Its effects are opposite that of a diuretic. The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Antidiuretic hormones are present in high concentrations under conditions of dehydration as a pathophysiological mechanism to promote water reabsorption. Both of those are also used exogenously as medications in people whose bodies need extra help with fluid balance via suppression of diuresis. In addition, there are va
Research
11,819 papers- Diabetes Insipidus and Syndrome of Inappropriate Antidiuretic Hormone in Critically Ill Patients.Critical care clinics · 2019
- Syndrome of Inappropriate Antidiuretic Hormone (SIADH).Clinical journal of oncology nursing · 2020
- Vasopressin antagonists.The New England journal of medicine · 2015
- Mirtazapine Risk of Hyponatremia and Syndrome of Inappropriate Antidiuretic Hormone Secretion in Adult and Elderly Patients: A Systematic Review.Cureus · 2021
- An Octopus-Derived Peptide with Antidiuretic Activity in Rats.Marine drugs · 2022
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An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, opposing diuresis. Its effects are opposite that of a diuretic. The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Antidiuretic hormones are present in high concentrations under conditions of dehydration as a pathophysiological mechanism to promote water reabsorption. Both of those are also used exogenously as medications in people whose bodies need extra help with fluid balance via suppression of diuresis. In addition, there are various other antidiuretic drugs, some molecularly close to ADH or oxytocin and others not. Antidiuretics reduce urine volume, particularly in diabetes insipidus (DI), which is one of their main indications.
The antidiuretic hormone class includes vasopressin (ADH), argipressin, desmopressin, lypressin, ornipressin, oxytocin, and terlipressin. Miscellaneous others include chlorpropamide and carbamazepine.
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