carbamazepin
Carbamazepine, sold under the brand name Tegretol among others, is an anticonvulsant medication used in the treatment of epilepsy and neuropathic pain. It is used as an adjunctive treatment in schizophrenia along with other medications and as a second-line agent in bipolar disorder. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.
Key facts
- Drug.KEGG
- D00252
- Drug.ChEMBL
- 108
- Drug.synonyms
- CBZ
- Drug.verifiedrevid
- 451682337
- Drug.image
- Carbamazepine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 175
- Drug.image2
- Carbamazepine-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 175
- Drug.tradename
- Tegretol, others
- Drug.MedlinePlus
- a682237
- Drug.DailyMedID
Article
14 sectionsContents
- Medical uses
- Adverse effects
- Pharmacogenetics
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- History
- Society and culture
- Environmental impact
- Brand names
- References
- Further reading
- External links
Carbamazepine, sold under the brand name Tegretol among others, is an anticonvulsant medication used in the treatment of epilepsy and neuropathic pain. It is used as an adjunctive treatment in schizophrenia along with other medications and as a second-line agent in bipolar disorder. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.
Carbamazepine was discovered in 1953 by Swiss chemist Walter Schindler. It was first marketed in 1962. It is available as a generic medication. It is on the World Health Organization's List of Essential Medicines. In 2023, it was the 185th most commonly prescribed medication in the United States, with more than 2million prescriptions.