ARHGAP5
Sign in to saveAlso known as GFI2, RhoGAP5, p190-B, p190BRhoGAP, Rho GTPase activating protein 5
Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene.
Gene data
ARHGAP5- Name
- Rho GTPase activating protein 5
- Type
- protein-coding
- Position
- 32,075,794–32,159,728 (+)
- Aliases
- GFI2, RhoGAP5, p190-B, p190BRhoGAP
- Ensembl
- ENSG00000100852
- RefSeq RNA
- NM_001030055.2, NM_001173.3
- RefSeq protein
- NP_001025226.1, NP_001164.2
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
Rho GTPase activating protein 5
- Symbol
- ARHGAP5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:32,075,794-32,159,728
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ARHGAP5 PDB 2EE4.png
Show 7 more facts
- HomoloGene ID
- 907
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/394
- genomic end
- 32628934
- genomic start
- 32545320
- chromosome
- human chromosome 14
- cytogenetic location
- 14q12
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene.
== Function ==
Excerpted from Wikipedia’s “ARHGAP5” article, available under the CC BY-SA 4.0 licence.