RND3
Sign in to saveAlso known as ARHE, Rho8, RhoE, memB, Rho family GTPase 3
Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3.
Gene data
RND3- Name
- Rho family GTPase 3
- Type
- protein-coding
- Position
- 150,468,195–150,539,011 (−)
- Aliases
- ARHE, Rho8, RhoE, memB
- Ensembl
- ENSG00000115963
- RefSeq RNA
- NM_001254738.1, NM_005168.5
- RefSeq protein
- NP_001241667.1, NP_005159.1
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
Rho family GTPase 3
- Symbol
- RND3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:150,468,195-150,539,011
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RND3 PDB 1gwn.png
Show 9 more facts
- HomoloGene ID
- 21074
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/390
- genomic end
- 151395525
- genomic start
- 151324709
- chromosome
- human chromosome 2
- cytogenetic location
- 2q23.3
- expressed in
- lactiferous duct
- Commons category
- RhoE (RND3)
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Regulation
- Interactions
- References
- Further reading
Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3.
Like other members of the Rho family of Ras-related GTPases it regulates the organization of the actin cytoskeleton in response to extracellular growth factors.
Excerpted from Wikipedia’s “RND3” article, available under the CC BY-SA 4.0 licence.