ASAP1
Sign in to saveAlso known as AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Genen från arten Homo sapiens
Gene data
ASAP1- Name
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
- Type
- protein-coding
- Position
- 130,052,104–130,444,082 (−)
- Aliases
- AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P
- Ensembl
- ENSG00000153317
- RefSeq RNA
- NM_001247996.2, NM_001362924.1, NM_001362925.2, NM_001362926.2, NM_018482.4
- RefSeq protein
- NP_001234925.1, NP_001349853.1, NP_001349854.1, NP_001349855.1, NP_060952.2
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Gene Ontology
Biological process
Pathways
Endocytosis - Homo sapiens (human)Fc gamma R-mediated phagocytosis - Homo sapiens (human)Organelle biogenesis and maintenanceOrganelle biogenesis and maintenanceCilium AssemblyCilium AssemblyVxPx cargo-targeting to ciliumVxPx cargo-targeting to ciliumCargo trafficking to the periciliary membraneCargo trafficking to the periciliary membrane
via MyGene.info
Gene · Ensembl
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
- Symbol
- ASAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:130,052,104-130,444,082
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein DDEF1 PDB 2da0.png
Show 7 more facts
- HomoloGene ID
- 7684
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/50807
- genomic end
- 130443674
- genomic start
- 131064353
- chromosome
- human chromosome 8
- cytogenetic location
- 8q24.21-q24.22
Sources (3)
via Wikidata · CC0