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GeneQ18039855· pop 7· linked from 2 articles

DDEF1

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Also known as AMAP1, CENTB4, PAG2, PAP, ZG14P, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

جين من أنواع جينات الإنسان العاقل

In the Vinony graph

Vinony's link graph records 2 inbound references to DDEF1, and connects out to PubMed, human chromosome 8 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 8.

Vinony links it to 6 Wikipedia language editions.

Gene data

ASAP1

Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Type: protein-coding
Position: 130,052,104–130,444,082 (−)
Aliases: AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P
Ensembl: ENSG00000153317
RefSeq RNA: NM_001247996.2, NM_001362924.1, NM_001362925.2, NM_001362926.2, NM_018482.4
RefSeq protein: NP_001234925.1, NP_001349853.1, NP_001349854.1, NP_001349855.1, NP_060952.2

This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

Gene Ontology

Biological process

cilium assembly cilium assembly protein localization to cilium positive regulation of membrane tubulation

Molecular function

GTPase activator activity GTPase activator activity protein binding cadherin binding

Cellular component

Golgi membrane podosome cytoplasm Golgi apparatus Golgi apparatus Golgi apparatus cytosol plasma membrane

Pathways

Endocytosis - Homo sapiens (human)Fc gamma R-mediated phagocytosis - Homo sapiens (human)Organelle biogenesis and maintenance Organelle biogenesis and maintenance Cilium Assembly Cilium Assembly VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium Cargo trafficking to the periciliary membrane Cargo trafficking to the periciliary membrane

via MyGene.info

Gene · Ensembl

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Symbol: ASAP1
Biotype: Protein coding
Organism: Homo sapiens
Location: 8:130,052,104-130,444,082
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein DDEF1 PDB 2da0.png

Show 7 more facts

HomoloGene ID: 7684
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/50807
genomic end: 130443674
genomic start: 131064353
chromosome: human chromosome 8
cytogenetic location: 8q24.21-q24.22

Sources (3)

via Wikidata · CC0

Article · العربية

DDEF1‏ (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1) هوَ بروتين يُشَفر بواسطة جين DDEF1 في الإنسان.

Abstract from DBpedia / Wikipedia · CC BY-SA

Available in 6 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 8