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astatine
Sign in to saveAlso known as At, element 85
Astatine is a chemical element; it has symbol At and atomic number 85. It is the rarest naturally occurring element in the Earth's crust, occurring only as the decay product of various heavier elements. All of astatine's isotopes are short-lived; the most stable is astatine-210, with a half-life of 8.1 hours. Consequently, a solid sample of the element has never been seen, because any macroscopic specimen would be immediately vaporized by the heat of its radioactivity.
OverviewAI-generated
Astatine is a chemical element with the symbol At and atomic number 85. Its chemical formula is At. The element has an electronegativity of 2.2 and a boiling point of 503. It was discovered in 1940. The Unicode character for astatine is 砈.
The standard atomic weight of astatine is 209.98715. It has a topological polar surface area of 0 and carries a charge of 0. There are no hydrogen bond donors or acceptors associated with the element. The InChIKey for astatine is RYXHOMYVWAEKHL-UHFFFAOYSA-N.
Astatine is referenced by 429 other encyclopedia articles. PubMed contains 619 entries related to the subject.
Synthesized by Vinony from 22 facts across 4 sources: Wikidata, PubChem, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- At
- Molecular weight
- 209.98715 g/mol
- IUPAC name
- astatine
- SMILES
- [At]
- InChIKey
- RYXHOMYVWAEKHL-UHFFFAOYSA-N
- Polar surface area
- 0 Ų
- H-bond donors
- 0
- H-bond acceptors
- 0
- Formal charge
- 0
via PubChem
Research
619 papers- Astatine-211 and actinium-225: two promising nuclides in targeted alpha therapy.ReviewActa biochimica et biophysica Sinica · 2024Zuo D, Wang H, Yu B et al.DOI: 10.3724/abbs.2024206
- Astatine.ReviewJournal of labelled compounds & radiopharmaceuticals · 2018Meyer GJDOI: 10.1002/jlcr.3573
- Astatine-211 Radiopharmaceuticals; Status, Trends, and the Future.ReviewCurrent radiopharmaceuticals · 2024Rabiei M, Asadi M, Yousefnia HDOI: 10.2174/0118744710262325231025075638
- Astatine-211-Labeled Therapy Targeting Amino Acid Transporters: Overcoming Drug Resistance in Non-Small Cell Lung Cancer.ReviewInternational journal of molecular sciences · 2025Feng S, Hisada K, Yorifuji H et al.DOI: 10.3390/ijms262110736
- Astatine-211: production and availability.ReviewCurrent radiopharmaceuticals · 2011Zalutsky MR, Pruszynski MDOI: 10.2174/1874471011104030177
- Realizing Clinical Trials with Astatine-211: The Chemistry Infrastructure.ReviewCancer biotherapy & radiopharmaceuticals · 2020Lindegren S, Albertsson P, Bäck T et al.DOI: 10.1089/cbr.2019.3055
- Astatine-211-Towards In Vivo Stable Astatine-211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications.ReviewMedicinal research reviews · 2026Müller M, Pedersen NB, Shalgunov V et al.DOI: 10.1002/med.70008
- Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211.International journal of molecular sciences · 2024Kaneda-Nakashima K, Shirakami Y, Hisada K et al.DOI: 10.3390/ijms252212386
via PubMed
~35 min read
Encyclopedic overview
18 sectionsContents
- Characteristics
- Physical
- Chemical
- Compounds
- History
- Isotopes
- Natural occurrence
- Synthesis
- Formation
- Separation methods
- Dry
- Wet
- Uses and precautions
- See also
- Notes
- References
- Bibliography
- External links
Astatine is a chemical element; it has symbol At and atomic number 85. It is the rarest naturally occurring element in the Earth's crust, occurring only as the decay product of various heavier elements. All of astatine's isotopes are short-lived; the most stable is astatine-210, with a half-life of 8.1 hours. Consequently, a solid sample of the element has never been seen, because any macroscopic specimen would be immediately vaporized by the heat of its radioactivity.
The bulk properties of astatine are not known with certainty. Many of them have been estimated from its position on the periodic table as a heavier analog of fluorine, chlorine, bromine, and iodine, the four stable halogens. However, astatine also falls roughly along the dividing line between metals and nonmetals, and some metallic behavior has also been observed and predicted for it. Astatine is likely to have a dark or lustrous appearance and may be a semiconductor or possibly a metal. Chemically, several anionic species of astatine are known and most of its compounds resemble those of iodine, but it also sometimes displays metallic characteristics and shows some similarities to silver.
Excerpted from Wikipedia’s “astatine” article, available under the CC BY-SA 4.0 licence.
Gallery (164)
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