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azamethiphos

Structure via PubChem · Public domain (PubChem)

EntityQ793533· pop 11· linked from 205 articles

azamethiphos

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Also known as S-[(6-chloro-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl thiophosphate, 6-chloro-3-dimethoxyphosphinoylthiomethyl-1,3-oxazolo(4,5-b)pyridin-2(3H)-one, S-((6-Chloro-2,3-dihydro-2-oxo-1,3-oxazolo-(4,5-b)pyridin-3-yl)methyl) O,O-dimethyl phosphorothioate, S-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2H)-yl)methyl) O,O-dimethylphosphorothioate, S-6-chloro-2,3-dihydro-2-oxo-1,3-oxazolo(4,5-b)pyridin-3-ylmethyl O,O-dimethyl phosphorothioate

Azamethiphos is an organothiophosphate insecticide. It is a veterinary drug used in Atlantic salmon fish farming along with other fish in the Salmonid family to control parasites, specifically sea lice. It is also used as an insecticide in biocidal products in Europe.

Chemical data

Formula
C9H10ClN2O5PS
Molecular weight
324.68 g/mol
IUPAC name
6-chloro-3-(dimethoxyphosphorylsulfanylmethyl)-[1,3]oxazolo[4,5-b]pyridin-2-one

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

~4 min read

Encyclopedic overview

7 sections
Contents
  • Mode of action
  • Registration
  • Stability
  • Toxicity
  • Environmental toxicity
  • Health effects due to exposure
  • References

Azamethiphos is an organothiophosphate insecticide. It is a veterinary drug used in Atlantic salmon fish farming along with other fish in the Salmonid family to control parasites, specifically sea lice. It is also used as an insecticide in biocidal products in Europe.

== Mode of action == Organophosphorus insecticides such as azamethiphos inhibit the action of the enzyme acetylcholinesterase. The acetylcholine, therefore, remains intact allowing the electrical signal to proceed without interruption. This phenomenon leads to overexcitation of the organism and eventually to the death of the insect.

Excerpted from Wikipedia’s “azamethiphos” article, available under the CC BY-SA 4.0 licence.