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bisoctrizole

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EntityQ4918369· pop 8· linked from 46 articles

bisoctrizole

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Also known as Tinosorb M, MBBT, UV-360

Bisoctrizole (INN/USAN, marketed by BASF as Tinosorb M, by DSM Nutritional Products as Parsol Max, by Everlight Chemical as Eversorb M, and by MPI as Milestab 360, INCI methylene bis-benzotriazolyl tetramethylbutylphenol) is a phenolic benzotriazole that is added to sunscreens to absorb UV rays. It is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. It also reflects and scatters UV.

Chemical data

Formula
C41H50N6O2
Molecular weight
658.9 g/mol
IUPAC name
2-(benzotriazol-2-yl)-6-[[3-(benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol
SMILES
CC(C)(C)CC(C)(C)C1=CC(=C(C(=C1)N2N=C3C=CC=CC3=N2)O)CC4=C(C(=CC(=C4)C(C)(C)CC(C)(C)C)N5N=C6C=CC=CC6=N5)O
InChIKey
FQUNFJULCYSSOP-UHFFFAOYSA-N
XLogP
12.8
Polar surface area
102 Ų
H-bond donors
2
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
urticaria

via ChEMBL · EBI

Wikidata facts

Mass
658.4
Show 3 more facts
chemical formula
C₄₁H₅₀N₆O₂
canonical SMILES
CC(C)(C)CC(C)(C)C1=CC(=C(C(=C1)N2N=C3C=CC=CC3=N2)O)CC4=C(C(=CC(=C4)C(C)(C)CC(C)(C)C)N5N=C6C=CC=CC6=N5)O
Commons category
Bisoctrizole
Sources (3)

via Wikidata · CC0

~2 min read

Encyclopedic overview

2 sections
Contents
  • References
  • External links

Bisoctrizole (INN/USAN, marketed by BASF as Tinosorb M, by DSM Nutritional Products as Parsol Max, by Everlight Chemical as Eversorb M, and by MPI as Milestab 360, INCI methylene bis-benzotriazolyl tetramethylbutylphenol) is a phenolic benzotriazole that is added to sunscreens to absorb UV rays. It is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. It also reflects and scatters UV.

Bisoctrizole is what is termed a hybrid UV absorber, which has been described as an organic UV filter produced in microfine organic particles (< 200&nbsp;nm), like microfine zinc oxide and titanium dioxide. Where other organic UV absorbers dissolved in either the oily or aqueous phases, bisoctrizole dissolves poorly in both.

Excerpted from Wikipedia’s “bisoctrizole” article, available under the CC BY-SA 4.0 licence.

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