calcipotriene

Key facts

Drug.Verifiedfields

changed

Drug.Watchedfields

changed

Drug.verifiedrevid

459992907

Drug.image

Calcipotriol.svg

Drug.image_class

skin-invert-image

Drug.image2

Calcipotriol-from-xtal-Mercury-3D-balls-thin.png

Drug.image_class2

bg-transparent

Drug.USAN

calcipotriene

Drug.tradename

Daivonex, others

Drug.MedlinePlus

a608018

Drug.DailyMedID

Calcipotriene

Drug.pregnancy_AU

B3

Drug.routes_of_administration

topical

Drug.ATC_prefix

D05

Drug.ATC_suffix

AX02

Drug.legal_AU

S4

Drug.legal_CA

Rx-only

Drug.legal_UK

POM

via Wikipedia infobox

Chemical data

Formula

C27H40O3

Molecular weight

412.6 g/mol

IUPAC name

trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

SMILES

C[C@H](/C=C/[C@H](C1CC1)O)[C@H]2CC[C@@H]\3[C@@]2(CCC/C3=C\C=C/4\C[C@H](C[C@@H](C4=C)O)O)C

InChIKey

LWQQLNNNIPYSNX-UROSTWAQSA-N

XLogP

4.3

Polar surface area

60.7 Ų

H-bond donors

3

H-bond acceptors

3

Formal charge

0

via PubChem

• Spotlight on calcipotriene/betamethasone dipropionate in psoriasis vulgaris of the trunk, limbs, and scalp.American journal of clinical dermatology · 2011
• The use of topical calcipotriene/calcipotriol in conditions other than plaque-type psoriasis.Journal of the American Academy of Dermatology · 1997
• Clinical Utility of Various Formulations of Calcipotriene and Betamethasone Dipropionate for the Treatment of Plaque Psoriasis in Patients Aged 12 Years or Older.Drug design, development and therapy · 2024
• Calcipotriol/calcipotriene (Dovonex/Daivonex) in combination with phototherapy: a review.Journal of the American Academy of Dermatology · 1997
• Topical application of calcipotriene and corticosteroids: combination regimens.Journal of the American Academy of Dermatology · 1997

via PubMed