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Vitamin B6 is a class of chemically related vitamins that your body needs to function properly. It plays important roles in brain development, immune function, and helping your body process proteins and other nutrients from food.
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Research
23,356 papers- Inflammation, vitamin B6 and related pathways.ReviewMolecular aspects of medicine · 2017Ueland PM, McCann A, Midttun Ø et al.DOI: 10.1016/j.mam.2016.08.001
- Vitamin B6 in Health and Disease.ReviewNutrients · 2021Stach K, Stach W, Augoff KDOI: 10.3390/nu13093229
- Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms.ReviewInternational journal of molecular sciences · 2020Mascolo E, Vernì FDOI: 10.3390/ijms21103669
- Does Vitamin B6 Act as an Exercise Mimetic in Skeletal Muscle?ReviewInternational journal of molecular sciences · 2024Kato N, Yang Y, Bumrungkit C et al.DOI: 10.3390/ijms25189962
- Vitamin B6 metabolism in microbes and approaches for fermentative production.ReviewBiotechnology advances · 2017Rosenberg J, Ischebeck T, Commichau FMDOI: 10.1016/j.biotechadv.2016.11.004
- The Role of Vitamin B6 in Women's Health.ReviewThe Nursing clinics of North America · 2021Lee ASDDOI: 10.1016/j.cnur.2020.10.002
- Emerging cardioprotective mechanisms of vitamin B6: a narrative review.ReviewEuropean journal of nutrition · 2022Kumrungsee T, Peipei Zhang, Yanaka N et al.DOI: 10.1007/s00394-021-02665-2
- Vitamin B6 status, deficiency and its consequences--an overview.ReviewNutricion hospitalaria · 2007Spinneker A, Sola R, Lemmen V et al.
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Encyclopedic overview
Vitamin B6 is one of the B vitamins, and is an essential nutrient for humans. The term essential nutrient refers to a group of six chemically similar compounds, i.e., "vitamers", which can be interconverted in biological systems. Its active form, pyridoxal 5′-phosphate, serves as a coenzyme in more than 140 enzyme reactions in amino acid, glucose, and lipid metabolism.
Plants synthesize pyridoxine as a means of protection from the UV-B radiation found in sunlight and for the role it plays in the synthesis of chlorophyll. Animals cannot synthesize any of the various forms of the vitamin, and hence must obtain it via diet, either of plants, or of other animals. There is some absorption of the vitamin produced by intestinal bacteria, but this is not sufficient to meet dietary needs. For adult humans, recommendations from various countries' food regulatory agencies are in the range of 1.0 to 2.0 milligrams (mg) per day. These same agencies also recognize ill effects from intakes that are too high, and so set safe upper limits, ranging from as low as 12 mg/day to as high as 100 mg/day depending on the country. Beef, pork, fowl and fish are generally good sources; dairy, eggs, mollusks and crustaceans also contain vitamin B6, but at lower levels. There is enough in a wide variety of plant foods so that a vegetarian or vegan diet does not put consumers at risk for deficiency.
Excerpted from Wikipedia’s “vitamin B6” article, available under the CC BY-SA 4.0 licence.