CCNT2

Name

cyclin T2

Type

protein-coding

Position

134,918,235–134,999,446 (+)

Aliases

CYCT2

Ensembl

ENSG00000082258

RefSeq RNA

NM_001241.4, NM_001320748.2, NM_001320749.2, NM_058241.3, NR_037649.2

RefSeq protein

NP_001232.1, NP_001307677.1, NP_001307678.1, NP_490595.1, XP_016860716.1

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010].

via MyGene.info

Gene · Ensembl

cyclin T2

Symbol

CCNT2

Biotype

Protein coding

Organism

Homo sapiens

Location

2:134,918,235-134,999,446

Strand

Forward (+)

Assembly

GRCh38