کیموزین
Sign in to saveAlso known as Chymosin, Cym, embryonic pepsinogen
Chymosin or rennin is a protease found in rennet. It is an aspartic endopeptidase belonging to MEROPS A1 family. It is produced by newborn ruminant animals in the lining of the abomasum to curdle the milk they ingest, allowing a longer residence in the bowels and better absorption. It is widely used in the production of cheese.
Key facts
- Enzyme.Name
- Chymosin
- Enzyme.EC_number
- 3.4.23.4
- Enzyme.CAS_number
- 9001-98-3
- Enzyme.GO_code
- 0030602
- Enzyme.image
- CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972.jpg
- Enzyme.caption
- Crystal structure of bovine chymosin complex with the inhibitor CP-113972.
- Nonhuman protein.Name
- Chymosin [Precursor]
- Nonhuman protein.caption
- X-ray analysis of calf chymosin
- Nonhuman protein.image
- X-RAY ANALYSES OF ASPARTIC PROTEINASES IV. STRUCTURE AND REFINEMENT AT 2.2 ANGSTROMS RESOLUTION OF BOVINE CHYMOSIN.jpg
- Nonhuman protein.Organism
- Bos taurus
- Nonhuman protein.Symbol
- Cym
- Nonhuman protein.AltSymbols
- CPC
- Nonhuman protein.EntrezGene
- 529879
- Nonhuman protein.UniProt
- P00794
- Nonhuman protein.PDB
- 4CMS
- Protein.Name
- chymosin pseudogene (human)
- Protein.HGNCid
- 2588
- Protein.Symbol
- CYMP
via Wikipedia infobox
Protein · UniProt
Pepsin A
- Gene
- Cym
- Organism
- Mus musculus (Mouse)
- Length
- 379 aa
- Molecular mass
- 42,511 Da
- Evidence
- 2: Evidence at transcript level
Aspartyl proteaseDisulfide bondHydrolaseProteaseSignalZymogen
View on UniProt →
Swiss-Prot (reviewed) · via UniProt
Research
1,306 papers- Chymosin: a short review on foetal and neonatal gastric proteases.Scandinavian journal of clinical and laboratory investigation. Supplementum · 1992
- Chymosin and other milk coagulants: sources and biotechnological interventions.Critical reviews in biotechnology · 2010
- Chymosin pretreatment accelerated papain catalysed hydrolysis for decreasing casein antigenicity by exposing the cleavage site at tyrosine residues.Food chemistry · 2023
- Stimulation of chymosin secretion by simultaneous expression with chymosin-binding llama single-domain antibody fragments in yeast.Applied microbiology and biotechnology · 2002
- A novel electrochemical assay for chymosin determination using a label-free peptide as a substrate.Journal of dairy science · 2021
via PubMed
Wikidata facts
- Instance of
- protein
- Subclass of
- peptidase
- Image
- X-RAY ANALYSES OF ASPARTIC PROTEINASES IV. STRUCTURE AND REFINEMENT AT 2.2 ANGSTROMS RESOLUTION OF BOVINE CHYMOSIN.jpg
Show 4 more facts
- EC enzyme number
- 3.4.23.4
- found in taxon
- house mouse
- biological process
- protein catabolic process
- Commons category
- Chymosin (synonym: renin)
via Wikidata · CC0