renin
Sign in to saveRenin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS), which increases the volume of extracellular fluid (blood plasma, lymph, and interstitial fluid) and causes arterial vasoconstriction. Thus, it increases the body's mean arterial blood pressure.
Key facts
- Enzyme.Name
- renin
- Enzyme.EC_number
- 3.4.23.15
- Enzyme.CAS_number
- 9015-94-5
- Enzyme.GO_code
- 0004195
via Wikipedia infobox
Article
13 sectionsContents
- Biochemistry and physiology
- Structure
- Secretion
- Renin–angiotensin system
- Function
- Genetics
- Clinical applications
- Measurement
- Discovery and naming
- See also
- References
- Further reading
- External links
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS), which increases the volume of extracellular fluid (blood plasma, lymph, and interstitial fluid) and causes arterial vasoconstriction. Thus, it increases the body's mean arterial blood pressure.
Renin is not commonly referred to as a hormone, although it has a receptor, the (pro)renin receptor, also known as the renin receptor and prorenin receptor (see also below), as well as enzymatic activity with which it hydrolyzes angiotensinogen to angiotensin I.